Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194672 | 0.85 | TSHR (0.41) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9812541 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL27669945 | 0.80 | MEN1 (0.57) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL24920165 | 0.79 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL12445692 | 0.79 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11232852 | 0.77 | KMT2A (0.47) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL135077 | 0.77 | MEN1 (0.61) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL9835270 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1TSHRCYP2C9 | |
| SCHEMBL1694806 | 0.76 | — | — | |
| SCHEMBL6992317 | 0.76 | TSHR (0.39) | MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827423-B1 | FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORP (US) | 2007-12-12 | — | — | EP | claimed |