Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123164 | 1.00 | SIRT5 (0.37) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3227645 | 1.00 | SIRT5 (0.37) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3123178 | 1.00 | SIRT5 (0.37) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3117506 | 0.98 | SIRT5 (0.40) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3117516 | 0.98 | SIRT5 (0.40) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3109524 | 0.85 | HDAC4 (0.35) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3109532 | 0.85 | HDAC4 (0.35) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3114392 | 0.83 | SIRT5 (0.42) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3122773 | 0.83 | SIRT5 (0.38) | SIRT5CA1CA2HDAC4HDAC1 | |
| SCHEMBL3122762 | 0.83 | SIRT5 (0.38) | SIRT5CA1CA2HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-B1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2010-04-07 | — | — | EP | disclosed |