SCHEMBL3227787

SCHEMBL3227787

CC(C)CC(C)(C)CC(O)CC(O)CO

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8402374 0.83 TSHR (0.32) TSHR
SCHEMBL496502 0.75 TDP1 (0.43) LMNATSHRALDH1A1TDP1
SCHEMBL24292513 0.74
SCHEMBL20548273 0.73 TSHR (0.30) TSHR
SCHEMBL13249198 0.72 TSHR (0.31) TSHR
SCHEMBL10457077 0.71 ALDH1A1 (0.35) LMNATSHRALDH1A1TDP1
SCHEMBL7946649 0.71 MAPK1 (0.31) TSHR
SCHEMBL2625315 0.70
SCHEMBL271356 0.70
SCHEMBL28796528 0.70 TSHR (0.50) LMNATSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100062029-A1 Product for the Targeted Release of Active Substances LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2010-03-11 US disclosed
EP-1858387-B1 PRODUCT FOR THE TARGETED RELEASE OF TWO-COMPARTMENT ACTIVE SUBSTANCES SCS SKIN CARE SYSTEMS GMBH (DE) 2009-06-17 EP disclosed
US-20080145388-A1 cosmetic cleaning product for controlling release; two layers define a compartment between them, which contains the active substance and optionally a gas-releasing component; one is impermeable, and one is permeable to the active substance; single use for body care; glove shape LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2008-06-19 US disclosed
EP-1858387-A1 PRODUCT FOR THE TARGETED RELEASE OF TWO-COMPARTMENT ACTIVE SUBSTANCES SCS Skin Care Systems GmbH (DE) 2007-11-28 EP disclosed
EP-1859020-A1 PRODUCT FOR THE TARGETED RELEASE OF ACTIVE SUBSTANCES SCS Skin Care Systems GmbH (DE) 2007-11-28 EP disclosed
WO-2006097171-A1 PRODUCT FOR THE TARGETED RELEASE OF ACTIVE SUBSTANCES SCS SKIN CARE SYSTEMS GMBH (DE) 2006-09-21 WO disclosed
WO-2006097170-A1 PRODUCT FOR THE TARGETED RELEASE OF TWO-COMPARTMENT ACTIVE SUBSTANCES SCS SKIN CARE SYSTEMS GMBH (DE) 2006-09-21 WO disclosed