Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421988 | 0.76 | KMT2A (0.56) | — | |
| SCHEMBL9493336 | 0.76 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL9493456 | 0.72 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1628516 | 0.69 | CYP1A2 (0.46) | SLC6A4SLC6A3 | |
| SCHEMBL34468469 | 0.68 | CYP1A2 (0.48) | — | |
| SCHEMBL9492616 | 0.68 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9494213 | 0.66 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL9492481 | 0.66 | ALDH1A1 (0.48) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3235577 | 0.65 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3KDM2B | |
| SCHEMBL5829462 | 0.64 | SLC6A2 (0.52) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026208-A1 | 1-AZA-BICYCLO[3.3.1]NONANE OR -3-ENE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2010-03-11 | — | — | WO | disclosed |