Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635615 | 0.86 | SLC6A4 (0.37) | LMNASLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL26636833 | 0.86 | SLC6A4 (0.37) | LMNASLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL26635618 | 0.86 | SLC6A4 (0.37) | LMNASLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL27810438 | 0.82 | THRB (0.38) | ALDH1A1HPGDSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL12103645 | 0.82 | THRB (0.38) | ALDH1A1HPGDSLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL1295966 | 0.81 | THRB (0.38) | ALDH1A1SLC6A4SLC6A2SLC6A3MAPK1 | |
| Hydrochloric Acid SCHEMBL1295968 | 0.81 | THRB (0.38) | ALDH1A1SLC6A4SLC6A2SLC6A3MAPK1 | |
| SCHEMBL12103606 | 0.77 | MAPK1 (0.41) | ALDH1A1SLC6A4SLC6A2MAPK1 | |
| SCHEMBL27810440 | 0.77 | MAPK1 (0.41) | ALDH1A1SLC6A4SLC6A2MAPK1 | |
| Hydrochloric Acid SCHEMBL1295995 | 0.76 | MAPK1 (0.40) | ALDH1A1SLC6A4SLC6A2SLC6A3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004343-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |