SCHEMBL3228295

SCHEMBL3228295

CCOC(=O)N(C)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
LMNA P02545 3/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
TRPA1 O75762 1/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28032845 0.86 ALDH1A1 (0.35) ALDH1A1LMNAKMT2AHSD17B10MEN1
SCHEMBL6203840 0.84 ALDH1A1 (0.39) ALDH1A1LMNAKMT2AHPGDTSHR
SCHEMBL7165884 0.82 GAA (0.44) ALDH1A1LMNAKMT2AHSD17B10MEN1
SCHEMBL26663647 0.81 CYP1A2 (0.39) ALDH1A1LMNAKMT2AHSD17B10MEN1
SCHEMBL14559286 0.81 ALDH1A1 (0.36) ALDH1A1LMNAKMT2AHSD17B10MEN1
SCHEMBL872502 0.80
SCHEMBL6053661 0.80
SCHEMBL11485752 0.79 TSHR (0.37) ALDH1A1LMNAKMT2AHSD17B10MEN1
SCHEMBL27600862 0.78 ALDH1A1 (0.42) ALDH1A1LMNAKMT2AHSD17B10MEN1
SCHEMBL10371717 0.78 ALDH1A1 (0.51) ALDH1A1LMNAKMT2AHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100068480-A1 Negative-working photosensitive resin composition and photosensitive resin plate using the same CITICORP NORTH AMERICA, INC., AS AGENT 2010-03-18 US disclosed
US-20090068413-A1 Negative-working photosensitive resin composition and photosensitive resin plate using the same TAKANASHI HIROSHI 2009-03-12 US disclosed
US-20080167444-A1 Abc Transporter Inhibitor SUNTORY LIMITED (JP) 2008-07-10 US disclosed
US-20060275702-A1 Negative-working photosensitive resin composition and photosensitive resin plate using the same TAKANASHI HIROSHI 2006-12-07 US disclosed
EP-1721901-A1 ABC TRANSPORTER INHIBITOR SUNTORY LIMITED (JP) 2006-11-15 EP disclosed
US-20060057495-A1 Negative-working photosensitive resin composition and photosensitive resin plate using the same TAKANASHI HIROSHI 2006-03-16 US disclosed
EP-1503994-A1 SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES Bayer CropScience AG (DE) 2005-02-09 EP disclosed
WO-2003093244-A1 SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES BAYER CROPSCIENCE AG (DE) 2003-11-13 WO disclosed
US-20010019811-A1 Negative-working photosensitive resin composition and photosensitive resin plate using the same TAKANASHI HIROSHI (JP) 2001-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167444-A1 Abc Transporter Inhibitor SLC47A1, ABCC1, SLC47A2 ALDH1A1 2914/4885LMNA 3055/4885KMT2A 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.