SCHEMBL3228433

SCHEMBL3228433

CC(O)(CBr)CCOP(=O)(O)OP(=O)(O)OCCC(C)(O)CBr

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MVD P53602 3/20 0.40
BTN3A1 O00481 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3003035 0.98 MVD (0.39) MVDBTN3A1
Bromohydrin Triphosphate SCHEMBL2034171 0.93 MVD (0.46) MVDBTN3A1
Bromohydrin Pyrophosphate SCHEMBL4309089 0.93 MVD (0.48) MVDBTN3A1
Bromohydrin Pyrophosphate SCHEMBL2968174 0.93 MVD (0.48) MVDBTN3A1
Bromohydrin Pyrophosphate SCHEMBL2037203 0.93 MVD (0.48) MVDBTN3A1
SCHEMBL13101843 0.91 MVD (0.37) MVDBTN3A1
SCHEMBL3003036 0.87 MVD (0.40) MVDBTN3A1
SCHEMBL21068019 0.85 LPAR3 (0.39) MVD
SCHEMBL4309091 0.85 LPAR3 (0.39) MVD
SCHEMBL4309087 0.83 CYP3A4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100068179-A1 Phosphohalohydrins, Process For The Production Thereof And Use Thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2010-03-18 US disclosed
US-7625879-B2 Phosphohalohydrins, process for the production thereof and use thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2009-12-01 US disclosed
US-20060287281-A1 Phosphohalohydrins, process for the production thereof and use thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2006-12-21 US disclosed
US-7109183-B2 Phosphohalohydrins, process for the production thereof and use thereof Institut National de la Sante et de la Recherchik Medicale (FR) 2006-09-19 US disclosed
US-20040087555-A1 Phosphohalohydrins, process for the production thereof and use thereof INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICATE (FR) 2004-05-06 US disclosed
US-6660723-B1 Activating primate gamma delta lymphocytes INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2003-12-09 US disclosed
EP-1109817-B1 PHOSPHOHALOHYDRINS, METHOD FOR MAKING SAME AND USES INST NAT SANTE RECH MED (FR) 2002-06-05 EP disclosed
EP-1109817-A1 PHOSPHOHALOHYDRINS, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2001-06-27 EP disclosed
WO-2000012516-A1 PHOSPHOHALOHYDRINS, METHOD FOR MAKING SAME AND USES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2000-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087555-A1 Phosphohalohydrins, process for the production thereof and use thereof CD4, HRH3, HRH1 MVD 2341/4885BTN3A1 24/4885
US-20060287281-A1 Phosphohalohydrins, process for the production thereof and use thereof CD4, CCR9, BCL9 MVD 1563/4885BTN3A1 15/4885
US-20100068179-A1 Phosphohalohydrins, Process For The Production Thereof And Use Thereof CD4, CCR9, ICOS MVD 1784/4885BTN3A1 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.