Bromohydrin Pyrophosphate

Bromohydrin Pyrophosphate

SCHEMBL2968174

C[C@](O)(CBr)CCOP(=O)(O)OP(=O)(O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MVD P53602 4/20 0.48
BTN3A1 O00481 3/20 0.46
FNTA P49354 4/20 0.33
GGPS1 O95749 3/20 0.33
PGGT1B P53609 3/20 0.33
FNTB P49356 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromohydrin Pyrophosphate SCHEMBL4309089 1.00 MVD (0.48) MVDBTN3A1FNTAGGPS1PGGT1B
Bromohydrin Pyrophosphate SCHEMBL2037203 1.00 MVD (0.48) MVDBTN3A1FNTAGGPS1PGGT1B
Bromohydrin Triphosphate SCHEMBL2034171 0.97 MVD (0.46) MVDBTN3A1FNTAGGPS1PGGT1B
SCHEMBL3228433 0.93 MVD (0.40) MVDBTN3A1
SCHEMBL3003035 0.91 MVD (0.39) MVDBTN3A1
SCHEMBL3003036 0.91 MVD (0.40) MVDBTN3A1
SCHEMBL3215427 0.89 MVD (0.38) MVDBTN3A1
SCHEMBL13101843 0.88 MVD (0.37) MVDBTN3A1
SCHEMBL3228438 0.86 MVD (0.35) MVDBTN3A1
SCHEMBL21068019 0.85 LPAR3 (0.39) MVD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7776847-B2 Benzisothiazoles useful for treating or preventing HCV infection RIGEL PHARMACEUTICALS, INC. (US) 2010-08-17 US disclosed
EP-1863572-A2 NEW CLASS OF T CELLS ACTIVATORS AND USE THEREOF Innate Pharma (FR) 2007-12-12 EP disclosed
US-20060229294-A1 Benzisothiazoles useful for treating or preventing HCV infection RIGEL PHARMACEUTICALS, INC. (US) 2006-10-12 US disclosed
WO-2006103568-A2 NEW CLASS OF Ϝδ T CELLS ACTIVATORS AND USE THEREOF INNATE PHARMA (FR) 2006-10-05 WO disclosed
WO-2006067635-A2 USE OF Ϝδ T LYMPHOCYTE ACTIVATORS AS VACCINE ADJUVANT INNATE PHARMA S.A. (FR) 2006-06-29 WO disclosed
EP-1569656-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE Innate Pharma (FR) 2005-09-07 EP disclosed
WO-2004050096-A2 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229294-A1 Benzisothiazoles useful for treating or preventing HCV infection HAVCR2, ZC3HAV1, MAVS MVD 2944/4885BTN3A1 513/4885FNTA 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.