Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235773 | 0.92 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL3235794 | 0.79 | CHRNB2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL3240178 | 0.78 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL2958380 | 0.77 | CHRNB2 (0.41) | CHRNB2CHRNA4 | |
| SCHEMBL29851078 | 0.77 | GBA2 (0.40) | CHRNB2CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL3237253 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA4 | |
| SCHEMBL3237787 | 0.75 | EPHX1 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL3239147 | 0.73 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL20587819 | 0.72 | HTR2C (0.54) | — | |
| SCHEMBL3237302 | 0.71 | CHRNB2 (0.51) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028011-A1 | AMIDES OF DIAZABICYCLONONANES AND USES THEREOF | TARGACEPT, INC. (US) | 2010-03-11 | — | — | WO | disclosed |