Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.78 |
| ▸ | MMP9 | P14780 | 19/20 | 0.78 |
| ▸ | MMP14 | P50281 | 15/20 | 0.74 |
| ▸ | MMP1 | P03956 | 13/20 | 0.74 |
| ▸ | MMP3 | P08254 | 13/20 | 0.74 |
| ▸ | MMP13 | P45452 | 12/20 | 0.74 |
| ▸ | MMP16 | P51512 | 4/20 | 0.71 |
| ▸ | MMP8 | P22894 | 4/20 | 0.71 |
| ▸ | MMP12 | P39900 | 2/20 | 0.71 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | MMP7 | P09237 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12609294 | 0.87 | MMP2 (0.81) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL12609305 | 0.87 | MMP2 (0.81) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1783733 | 0.85 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1784100 | 0.85 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL27812748 | 0.84 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1785737 | 0.84 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL13738485 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL20214127 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL12605175 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1784722 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010080-A1 | ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS | BRACCO IMAGING SPA (IT) | 2010-01-28 | — | — | WO | disclosed |