Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | P2RY12 | Q9H244 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881773 | 0.86 | KDM4E (0.72) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL3225595 | 0.85 | P2RY12 (0.52) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL3226385 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL4099899 | 0.84 | KMT2A (0.57) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL3216575 | 0.84 | P2RY12 (0.69) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL4872943 | 0.84 | P2RY12 (0.57) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL4115190 | 0.84 | P2RY12 (0.70) | ALDH1A1KMT2AKDM4EMEN1P2RY12 | |
| SCHEMBL4874393 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL4103245 | 0.81 | P2RY12 (0.59) | ALDH1A1KMT2AKDM4EMEN1MAPK1 | |
| SCHEMBL4737008 | 0.80 | P2RY12 (0.58) | ALDH1A1KMT2AKDM4EMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005385-A1 | 2-AMINO-6-ALKYL SUBSTITUTED PYRIDINE DERIVATIVES USEFUL AS P2Y12 INHIBITORS 308 | ASTRAZENECA AB (SE) | 2010-01-14 | — | — | WO | disclosed |