Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064238 | 0.67 | HPGD (0.52) | HPGDNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL3841963 | 0.67 | — | — | |
| SCHEMBL9325539 | 0.67 | ALDH1A1 (0.38) | HPGDMAPTALDH1A1 | |
| SCHEMBL19356871 | 0.65 | MEN1 (0.33) | HPGDLMNAMAPTALDH1A1 | |
| SCHEMBL11018260 | 0.64 | ALDH1A1 (0.33) | HPGDKDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9638346 | 0.64 | NPC1 (0.41) | NPC1RAB9ALMNAMAPT | |
| SCHEMBL725505 | 0.63 | — | — | |
| SCHEMBL6112098 | 0.62 | HPGD (0.52) | HPGDNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL952325 | 0.61 | ALDH1A1 (0.56) | HPGDNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9160350 | 0.61 | DAO (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009847-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, METHOD FOR THE PRODUCTION THEREOF, AND USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-28 | — | — | WO | disclosed |
| EP-2147919-A1 | Heterocyclic substituted amides, method for their manufacture and their use as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2010-01-27 | — | — | EP | disclosed |