SCHEMBL3229773

SCHEMBL3229773

O=c1[nH]cc(C#Cc2cccc(OP(=O)(O)OP(=O)(O)OP(=O)(O)O)c2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 13/20 0.37
P2RY6 Q15077 4/20 0.37
P2RY14 Q15391 3/20 0.35
P2RY4 P51582 2/20 0.35
B4GALT1 P15291 1/20 0.34
SLC5A2 P31639 2/20 0.33
GPR17 Q13304 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3238083 0.78 SLC5A2 (0.41) SLC5A2
SCHEMBL1998514 0.75 P2RY2 (0.44) P2RY2P2RY6P2RY4GPR17
SCHEMBL3236533 0.71 PNP (0.36) SLC5A2
Triphosphate SCHEMBL27986622 0.71 P2RY14 (0.44) P2RY2P2RY6P2RY14P2RY4B4GALT1
Triphosphate SCHEMBL27947675 0.71 P2RY14 (0.44) P2RY2P2RY6P2RY14P2RY4B4GALT1
Triphosphate SCHEMBL30097807 0.71 P2RY14 (0.44) P2RY2P2RY6P2RY14P2RY4B4GALT1
SCHEMBL3238072 0.69 P2RY2 (0.49) P2RY2P2RY6P2RY4
SCHEMBL3238028 0.66 P2RY2 (0.44) P2RY2P2RY6P2RY4
SCHEMBL3239087 0.66 PNP (0.33) SLC5A2
SCHEMBL1996325 0.65 PNP (0.43) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1544294-B1 NUCLEOSIDES OR NUCLEOTIDES HAVING NOVEL UNNATURAL BASES AND USE THEREOF RIKEN (JP) 2013-04-10 EP disclosed
US-7745417-B2 Nucleosides or nucleotides having novel unnatural bases and use thereof RIKEN (JP) 2010-06-29 US disclosed
US-20060263771-A1 Nucleoside or nucleotides having novel unnatural bases and utilization of the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2006-11-23 US disclosed
EP-1544294-A1 NUCLEOSIDES OR NUCLEOTIDES HAVING NOVEL UNNATURAL BASES AND USE THEREOF Riken (JP) 2005-06-22 EP disclosed