Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 6/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.35 |
| ▸ | UMPS | P11172 | 1/20 | 0.33 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238083 | 0.85 | SLC5A2 (0.41) | SLC5A2MAPTCYP3A4 | |
| SCHEMBL1998514 | 0.80 | P2RY2 (0.44) | — | |
| SCHEMBL3239087 | 0.79 | PNP (0.33) | PNPSLC5A2UMPSSYNJ2KDM4E | |
| SCHEMBL3236641 | 0.77 | PNP (0.36) | PNPSLC5A2UMPS | |
| SCHEMBL3236631 | 0.77 | PNP (0.36) | PNPSLC5A2UMPS | |
| SCHEMBL1996325 | 0.76 | PNP (0.43) | PNPSLC5A2SYNJ2KDM4EGMNN | |
| SCHEMBL3231325 | 0.75 | SLC5A2 (0.38) | PNPSLC5A2KDM4E | |
| SCHEMBL3229773 | 0.71 | P2RY2 (0.37) | SLC5A2 | |
| SCHEMBL10764781 | 0.69 | PNP (0.44) | PNPSLC5A2UMPSHIF1A | |
| SCHEMBL16620686 | 0.69 | SLC5A2 (0.40) | PNPSLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745417-B2 | Nucleosides or nucleotides having novel unnatural bases and use thereof | RIKEN (JP) | 2010-06-29 | — | — | US | claimed |
| EP-1544294-B1 | NUCLEOSIDES OR NUCLEOTIDES HAVING NOVEL UNNATURAL BASES AND USE THEREOF | RIKEN (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-7745417-B2 | Nucleosides or nucleotides having novel unnatural bases and use thereof | RIKEN (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20060263771-A1 | Nucleoside or nucleotides having novel unnatural bases and utilization of the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-11-23 | — | — | US | disclosed |
| EP-1544294-A1 | NUCLEOSIDES OR NUCLEOTIDES HAVING NOVEL UNNATURAL BASES AND USE THEREOF | Riken (JP) | 2005-06-22 | — | — | EP | disclosed |