SCHEMBL3229780

SCHEMBL3229780

NC(=O)c1nc(NC(=O)C2O[C@H](CO)[C@@H](O)[C@H]2OP(=O)(O)O)c[nH]1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.38
FBP1 P09467 1/20 0.32
ATIC P31939 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574712 0.86 ADORA1 (0.39) ADORA1
SCHEMBL860142 0.76 ADORA1 (0.37) ADORA1
SCHEMBL4317020 0.75 ADORA1 (0.40) ADORA1
SCHEMBL5369246 0.73 P2RY14 (0.39) ADORA1
SCHEMBL1062463 0.72 ADORA1 (0.40) ADORA1
SCHEMBL29068760 0.72 ADORA1 (0.41) ADORA1
SCHEMBL4899187 0.71 ADORA1 (0.38) ADORA1
SCHEMBL558715 0.71 ADORA1 (0.39) ADORA1CYP2C19HIF1A
SCHEMBL9893437 0.69 ADORA1 (0.35) ADORA1
SCHEMBL430834 0.69 ADORA1 (0.44) ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010017526-A1 PURINE NUCLEOTIDES ISOTOPICALLY LABELED IN THE PURINE BASE, METHODS OF MAKING THEREOF AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2010-02-11 WO disclosed