SCHEMBL860142

SCHEMBL860142

O=C(O)c1nc(NC2O[C@H](CO)[C@@H](O)[C@H]2OP(=O)(O)O)c[nH]1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.37
FGF1 P05230 1/20 0.33
FGF2 P09038 1/20 0.33
VEGFA P15692 1/20 0.33
HPSE Q9Y251 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574712 0.91 ADORA1 (0.39) ADORA1
SCHEMBL5245060 0.78 ADORA1 (0.38) ADORA1
SCHEMBL29068760 0.77 ADORA1 (0.41) ADORA1
SCHEMBL3229780 0.76 ADORA1 (0.38) ADORA1
SCHEMBL263892 0.73 ADORA1 (0.41) ADORA1
SCHEMBL769262 0.73 ADORA1 (0.45) ADORA1FGF1FGF2VEGFAHPSE
SCHEMBL379657 0.73 ADORA1 (0.41) ADORA1FGF1FGF2VEGFAHPSE
SCHEMBL783243 0.70 LGALS8 (0.41) ADORA1
SCHEMBL3749134 0.69 P2RY2 (0.37)
SCHEMBL3691849 0.69 ADORA1 (0.37) ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2079837-B1 METHOD FOR OBTAINING VARIANTS OF LACTIC BACTERIA USEFUL IN THE PRODUCTION OF VITAMIN K2 AND APPLICATIONS FOR THE PREPARATION OF FOOD PRODUCTS GERVAIS DANONE SA (FR) 2014-06-04 EP claimed
US-20210363239-A1 MODIFIED MEMBRANE SPANNING PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF Abilita Bio, Inc. 2021-11-25 US disclosed
US-11053312-B2 Modified membrane spanning proteins and methods for the preparation and use thereof Abilita Bio, Inc. (US) 2021-07-06 US disclosed
EP-2463654-B1 Compositions and methods for modeling saccharomyces cerevisiae metabolism UNIV CALIFORNIA (US) 2020-06-03 EP disclosed
US-20190263902-A1 MODIFIED MEMBRANE SPANNING PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF Abilita Bio, Inc. 2019-08-29 US disclosed
EP-3212784-B1 MODIFIED MEMBRANE SPANNING PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF ABILITA BIO INC (US) 2019-05-29 EP disclosed
US-10287349-B2 Modified membrane spanning proteins and methods for the preparation and use thereof Abilita Bio, Inc. (US) 2019-05-14 US disclosed
EP-1683866-B1 Deletion forms of IgE-dependent histamine releasing factor having histamine-releasing activity, HRF-binding peptides and the uses thereof EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUND (KR) 2017-03-01 EP disclosed
US-20160123956-A1 MODIFIED MEMBRANE SPANNING PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF Abilita Bio, Inc. 2016-05-05 US disclosed
EP-2463654-A1 Compositions and methods for modeling saccharomyces cerevisiae metabolism The Regents of The University of California (US) 2012-06-13 EP disclosed
US-8170852-B2 Data structures and methods for modeling Saccharomyces cerevisiae metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-01 US disclosed
EP-2434421-A2 Compositions and methods for modeling saccharomyces cerevisiae metabolism The Regents of The University of California (US) 2012-03-28 EP disclosed
US-20100280803-A1 Compositions and Methods for Modeling Saccharomyces cerevisiae Metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2010-11-04 US disclosed
US-7772368-B2 Deletion forms of IGE-dependent histamine releasing factor having histamine releasing activity, HRF-binding peptides and the uses thereof EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2010-08-10 US disclosed
US-7751981-B2 Articles of manufacture and methods for modeling Saccharomyces cerevisiae metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-06 US disclosed
WO-2010017526-A1 PURINE NUCLEOTIDES ISOTOPICALLY LABELED IN THE PURINE BASE, METHODS OF MAKING THEREOF AND USES THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2010-02-11 WO disclosed
US-20060165677-A1 DELETION FORMS OF IgE-DEPENDENT HISTAMINE RELEASING FACTOR HAVING HISTAMINE RELEASING ACTIVITY, HRF-BINDING PEPTIDES AND THE USES THEREOF EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2006-07-27 US disclosed
EP-1683866-A2 Deletion forms of IgE-dependent histamine releasing factor having histamine-releasing activity, HRF-binding peptides and the uses thereof Ewha University-Industry Collaboration Foundation (KR) 2006-07-26 EP disclosed