SCHEMBL3229856

SCHEMBL3229856

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nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 2/20 0.35
PDE4A P27815 1/20 0.35
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2321352 1.00 LMNA (0.41) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL2317860 1.00 LMNA (0.41) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL2429499 1.00 LMNA (0.41) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL264710 1.00 LMNA (0.41) LMNAL3MBTL1TDP1KDM4EPDE4A
Sulfuric Acid SCHEMBL10602546 0.98 LMNA (0.39) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL28503116 0.98 LMNA (0.39) LMNAL3MBTL1TDP1KDM4EPDE4A
Methane SCHEMBL17748249 0.96 LMNA (0.38) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL3417631 0.84 LMNA (0.39) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL3415482 0.84 LMNA (0.39) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL3432829 0.84 LMNA (0.39) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010022461-A1 SULPHATED SUGARS TO INCREASE ACTIVITY OF SULPHATASES EN LYSOSOMAL STORAGE DISORDERS CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE (AU) 2010-03-04 WO claimed
EP-0348184-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1993-03-03 EP claimed
US-5185325-A Topical for inducing hair growth; using aldono- or aldurono-monolactones as glycosaminoglycanase inhibitors; powders, shampoo, creams, lotions CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-02-09 US claimed
EP-0348184-A2 Cosmetic composition UNILEVER PLC (GB) 1989-12-27 EP claimed
WO-2010022461-A1 SULPHATED SUGARS TO INCREASE ACTIVITY OF SULPHATASES EN LYSOSOMAL STORAGE DISORDERS CHILDREN, YOUTH AND WOMEN'S HEALTH SERVICE (AU) 2010-03-04 WO disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0490581-B1 Cosmetic composition UNILEVER PLC (GB) 1996-05-22 EP disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
EP-0375388-B1 Cosmetic composition UNILEVER PLC (GB) 1994-03-02 EP disclosed
EP-0580409-A2 Cosmetic composition containing DOPA derivatives UNILEVER PLC (GB) 1994-01-26 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed
EP-0571198-A1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1993-11-24 EP disclosed
EP-0490581-A1 Cosmetic composition UNILEVER PLC (GB) 1992-06-17 EP disclosed
US-5081151-A Applying a hexosaccharic acid, salt or ester CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-01-14 US disclosed
EP-0375388-A2 Cosmetic composition UNILEVER PLC (GB) 1990-06-27 EP disclosed
EP-0348184-A2 Cosmetic composition UNILEVER PLC (GB) 1989-12-27 EP disclosed