Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377899 | 0.90 | PKM (0.57) | PKMMAPK1HSD17B10EGFRALDH1A1 | |
| SCHEMBL9787311 | 0.88 | MAPK1 (0.59) | PKMMAPK1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL9858207 | 0.85 | PKM (0.54) | PKMMAPK1HSD17B10EGFRALDH1A1 | |
| SCHEMBL28519762 | 0.85 | TDP1 (0.57) | PKMMAPK1HSD17B10EGFRALDH1A1 | |
| SCHEMBL3295954 | 0.85 | TDP1 (0.57) | PKMMAPK1HSD17B10EGFRALDH1A1 | |
| SCHEMBL14273831 | 0.85 | TDP1 (0.57) | PKMMAPK1HSD17B10EGFRALDH1A1 | |
| Squalane SCHEMBL6425894 | 0.84 | TDP1 (0.56) | PKMMAPK1HSD17B10EGFRALDH1A1 | |
| SCHEMBL510609 | 0.84 | MAPT (0.49) | PKMMAPK1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL6024231 | 0.83 | SCN1A (0.58) | PKMMAPK1HSD17B10EGFRALDH1A1 | |
| SCHEMBL15449675 | 0.83 | SCN1A (0.58) | PKMMAPK1HSD17B10EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080193398-A1 | Derivatives of Heptaazaphenalene, Methods for Obtaining Them, and Their Use as Protecting Agents Against Uv Radiation | ISDIN, S.A. (ES) | 2008-08-14 | — | — | US | claimed |
| EP-1904500-A1 | NEW DERIVATIVES OF HEPTAAZAPHENALENE, METHODS FOR OBTAINING THEM, AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2008-04-02 | — | — | EP | claimed |
| WO-2007006807-A1 | NEW DERIVATIVES OF HEPTAAZAPHENALENE, METHODS FOR OBTAINING THEM, AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2007-01-18 | — | — | WO | claimed |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | disclosed |
| US-20080193398-A1 | Derivatives of Heptaazaphenalene, Methods for Obtaining Them, and Their Use as Protecting Agents Against Uv Radiation | ISDIN, S.A. (ES) | 2008-08-14 | — | — | US | disclosed |
| EP-1904500-A1 | NEW DERIVATIVES OF HEPTAAZAPHENALENE, METHODS FOR OBTAINING THEM, AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2008-04-02 | — | — | EP | disclosed |
| EP-1904487-A2 | INDOLE DERIVATIVES FOR THE TREATMENT OF TUBERCULOSIS | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006807-A1 | NEW DERIVATIVES OF HEPTAAZAPHENALENE, METHODS FOR OBTAINING THEM, AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006067392-A2 | INDOLE DERIVATIVES FOR THE TREATMENT OF TUBERCULOSIS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080193398-A1 | Derivatives of Heptaazaphenalene, Methods for Obtaining Them, and Their Use as Protecting Agents Against Uv Radiation | ERCC4, XPA, CYP51A1 | PKM 3674/4885MAPK1 4184/4885HSD17B10 109/4885 |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | UGT2B17, TACR2, UGT1A1 | PKM 2114/4885MAPK1 4141/4885HSD17B10 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.