Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223205 | 0.95 | TMEM97 (0.39) | TMEM97SIGMAR1UTS2RS1PR3P2RX3 | |
| SCHEMBL3234270 | 0.94 | TMEM97 (0.38) | TMEM97SIGMAR1UTS2RS1PR3P2RX3 | |
| SCHEMBL3234623 | 0.91 | TMEM97 (0.39) | TMEM97SIGMAR1UTS2RCHRM2CHRM4 | |
| SCHEMBL3232026 | 0.91 | TMEM97 (0.39) | TMEM97SIGMAR1UTS2RKDRCHRM2 | |
| SCHEMBL3227819 | 0.91 | TMEM97 (0.41) | TMEM97SIGMAR1CHRM2CHRM4HTR1A | |
| SCHEMBL4234564 | 0.91 | UTS2R (0.40) | TMEM97SIGMAR1UTS2RS1PR3SMN1; SMN2 | |
| SCHEMBL3219213 | 0.91 | SMN1; SMN2 (0.38) | TMEM97SIGMAR1UTS2RS1PR3SMN1; SMN2 | |
| SCHEMBL3227174 | 0.87 | UTS2R (0.41) | MCHR1TMEM97SIGMAR1UTS2RMEN1 | |
| SCHEMBL3227966 | 0.86 | UTS2R (0.42) | UTS2RS1PR3P2RX3 | |
| SCHEMBL4234963 | 0.86 | KIT (0.40) | TMEM97SIGMAR1UTS2RKDRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056522-A1 | INTRAOCULAR PRESSURE-LOWERING AGENT COMPRISING COMPOUND HAVING HISTONE DEACETYLASE INHIBITOR EFFECT AS ACTIVE INGREDIENT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056522-A1 | INTRAOCULAR PRESSURE-LOWERING AGENT COMPRISING COMPOUND HAVING HISTONE DEACETYLASE INHIBITOR EFFECT AS ACTIVE INGREDIENT | HDAC1, HDAC9, HDAC5 | MCHR1 3566/4885TMEM97 3579/4885SIGMAR1 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.