SCHEMBL3230337

SCHEMBL3230337

CC(C)(C)c1ccc(Oc2ccccc2C(=O)O)cc1.CCCCCCCCc1ccc(Oc2ccccc2C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 6/20 0.52
PLK3 Q9H4B4 4/20 0.52
PPARA Q07869 2/20 0.51
PPARG P37231 1/20 0.51
LPAR1 Q92633 3/20 0.49
STS P08842 2/20 0.49
LPAR3 Q9UBY5 1/20 0.49
AGTR1 P30556 1/20 0.48
AGTR2 P50052 1/20 0.48
PSEN1 P49768 1/20 0.48
PSEN2 P49810 1/20 0.48
APH1B Q8WW43 1/20 0.48
NCSTN Q92542 1/20 0.48
APH1A Q96BI3 1/20 0.48
PSENEN Q9NZ42 1/20 0.48
STAT3 P40763 1/20 0.47
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543492 0.92 PPARA (0.59) PLK1PLK3PPARAPPARGLPAR1
SCHEMBL8646631 0.92 PPARA (0.59) PLK1PLK3PPARAPPARGLPAR1
SCHEMBL4160313 0.86 AGTR1 (0.59) PLK1PLK3PPARAPPARGLPAR1
SCHEMBL3230338 0.85 PPARA (0.60) PLK1PLK3PPARAPPARGSTAT3
SCHEMBL294263 0.85 NPSR1 (0.56) MAPT
SCHEMBL29539667 0.85 NPSR1 (0.56) MAPT
Phthalic Acid SCHEMBL27847754 0.84 PLK1 (0.61) PLK1PLK3PPARAPPARGSTAT3
SCHEMBL10686662 0.84 NPSR1 (0.55) MAPT
Phthalic Acid SCHEMBL28084704 0.83 PLK1 (0.53) PLK1PLK3PPARAPPARGLPAR1
SCHEMBL699305 0.81 PSEN1 (0.49) PLK1LPAR1LPAR3AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2098569-B1 POLYACETAL RESIN COMPOSITION AND MOLDED ARTICLE THEREOF POLYPLASTICS CO (JP) 2014-11-26 EP disclosed
EP-2098568-B1 POLYACETAL RESIN COMPOSITION AND MOLDED ARTICLE THEREOF POLYPLASTICS CO (JP) 2013-05-01 EP disclosed
US-20100056676-A1 POLYACETAL RESIN COMPOSITION AND MOLDED ARTICLE THEREOF POLYPLASTICS CO.,LTD. (JP) 2010-03-04 US disclosed
EP-2098569-A1 POLYACETAL RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Polyplastics Co., Ltd. (JP) 2009-09-09 EP disclosed
EP-2098568-A1 POLYACETAL RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Polyplastics Co., Ltd. (JP) 2009-09-09 EP disclosed