Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241681 | 0.86 | MEN1 (0.50) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL3235788 | 0.86 | MEN1 (0.50) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL3240771 | 0.83 | MEN1 (0.48) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL3233845 | 0.80 | MEN1 (0.67) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL10355375 | 0.80 | MEN1 (0.64) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL2429794 | 0.78 | MEN1 (0.82) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL10468609 | 0.78 | KMT2A (0.56) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL6202771 | 0.76 | KMT2A (0.54) | MEN1KMT2ATDP1MAPTLMNA | |
| SCHEMBL10731153 | 0.76 | MEN1 (0.59) | MEN1KMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL10729559 | 0.76 | MEN1 (0.59) | MEN1KMT2ATDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029065-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |