Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233026 | 0.85 | MAPK1 (0.51) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL2161013 | 0.84 | MAPK1 (0.52) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL3240660 | 0.82 | MAPK1 (0.49) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL3233841 | 0.80 | MAPK1 (0.49) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL3245753 | 0.79 | MAPK1 (0.47) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL2170715 | 0.78 | MAPK1 (0.44) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL10513953 | 0.78 | MAPK1 (0.45) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL10510759 | 0.78 | MAPK1 (0.45) | MAPK1L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL3237155 | 0.77 | MAPK1 (0.39) | MAPK1TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL2315369 | 0.76 | MAPK1 (0.41) | MAPK1TDP1MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029065-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |