Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240660 | 0.95 | MAPK1 (0.49) | MAPK1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL3238214 | 0.93 | MAPK1 (0.39) | MAPK1DRD2GRM2 | |
| SCHEMBL3237508 | 0.91 | MAPK1 (0.36) | MAPK1KDM4EKMT2AMEN1CYP2C9 | |
| SCHEMBL3266419 | 0.88 | MAPK1 (0.40) | MAPK1KMT2AMEN1DRD2L3MBTL1 | |
| SCHEMBL10513953 | 0.87 | MAPK1 (0.45) | MAPK1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL10510759 | 0.87 | MAPK1 (0.45) | MAPK1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL3233897 | 0.86 | MAPK1 (0.38) | MAPK1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL3233841 | 0.85 | MAPK1 (0.49) | MAPK1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL3232029 | 0.80 | MAPK1 (0.46) | MAPK1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL2161013 | 0.80 | MAPK1 (0.52) | MAPK1KDM4EKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029066-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |