SCHEMBL323151

SCHEMBL323151

OCC1CCCC[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4162100 1.00
SCHEMBL1399909 1.00
SCHEMBL11877100 0.97
SCHEMBL75987 0.92
SCHEMBL385765 0.92
SCHEMBL384800 0.92
SCHEMBL1220462 0.80
SCHEMBL2916620 0.77
SCHEMBL3975826 0.77 NOS1 (0.31)
SCHEMBL3910385 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 701 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4389746-A2 P2X3 RECEPTOR ANTAGONISTS Recordati Industria Chimica E Farmaceutica SPA (IT) 2024-06-26 EP claimed
US-11999732-B2 P2X3 receptor antagonists RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2024-06-04 US claimed
US-20220388967-A1 Phenyl Amino Pyrimidine Compounds and Uses Thereof SIERRA ONCOLOGY, INC. (US) 2022-12-08 US claimed
CN-109689642-B Monocyclic heteroaryl substituted compounds 百时美施贵宝公司 2022-04-12 CN claimed
US-20210246139-A1 P2X3 RECEPTOR ANTAGONISTS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2021-08-12 US claimed
CN-110372657-B 7-O-acylamino substituted hesperetin derivative and preparation method and application thereof 安徽医科大学 2021-06-04 CN claimed
EP-3820566-A1 P2X3 RECEPTOR ANTAGONISTS Recordati Industria Chimica E Farmaceutica SPA (IT) 2021-05-19 EP claimed
CN-112584898-A P2X3Receptor antagonists 瑞蔻达蒂化学和制药工业股份有限公司 2021-03-30 CN claimed
CN-108558876-B Pyrazolo [3,4-b ] pyridine derivative and preparation method and application thereof 中南大学 2020-08-04 CN claimed
WO-2020011921-A1 P2X3 RECEPTOR ANTAGONISTS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2020-01-16 WO claimed
EP-0765865-A1 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION SEIKAGAKU CORPORATION (JP) 1997-04-02 EP claimed
US-5591737-A ELASTASE INHIBITORS MERCK & CO., INC. (US) 1997-01-07 US claimed
WO-1994010142-A1 NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1994-05-11 WO claimed
EP-0482119-A1 INTERCALATING AGENTS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1992-04-29 EP claimed
WO-1991000265-A1 INTERCALATING AGENTS CANCER RESEARCH TECHNOLOGY LTD. (GB) 1991-01-10 WO claimed
US-4925849-A DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-15 US claimed
EP-0299209-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-01-18 EP claimed
US-4315938-A ANTIDEPRESSANTS BOEHRINGER INGELHEIM GMBH (DE) 1982-02-16 US claimed
US-4101661-A PENICILLINS, CEPHALOSPORINS WARNER-LAMBERT (US) 1978-07-18 US claimed
US-4021551-A INDUCERS FOR INTERFERON FORMATION BOEHRINGER INGELHEIM GMBH (DT) 1977-05-03 US claimed