Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13494344 | 1.00 | ALOX5AP (0.48) | ALOX5APMEN1KMT2ATDP1CFTR | |
| SCHEMBL12391809 | 0.86 | TSHR (0.52) | ALOX5APMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1038904 | 0.86 | TSHR (0.52) | ALOX5APMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL3235521 | 0.84 | MEN1 (0.61) | ALOX5APMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3494747 | 0.84 | MEN1 (0.61) | ALOX5APMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13941834 | 0.77 | TP53 (0.68) | ALOX5APMEN1KMT2AALDH1A1GALR3 | |
| SCHEMBL13941829 | 0.77 | TP53 (0.68) | ALOX5APMEN1KMT2AALDH1A1GALR3 | |
| SCHEMBL13942115 | 0.76 | TSHR (0.74) | ALOX5APMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13942117 | 0.75 | ALOX5AP (0.65) | ALOX5APMEN1KMT2AHTTTSHR | |
| SCHEMBL1043674 | 0.74 | GNRHR (0.42) | ALOX5APGNRHRPPARGHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662581-B1 | Eg5 co-crystals | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-02-16 | — | — | US | disclosed |