Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 0.83 |
| ▸ | CLK1 | P49759 | 1/20 | 0.64 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233991 | 1.00 | PIM1 (0.83) | PIM1CLK1DYRK2 | |
| SCHEMBL28595477 | 0.91 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL29696854 | 0.84 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL7243809 | 0.84 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL14115819 | 0.84 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL4934423 | 0.83 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL29696924 | 0.83 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL14115818 | 0.83 | PIM1 (1.00) | PIM1CLK1DYRK2 | |
| SCHEMBL13535287 | 0.81 | PIM1 (0.76) | PIM1CLK1DYRK2 | |
| SCHEMBL29697027 | 0.81 | PIM1 (1.00) | PIM1CLK1DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010147-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-01-28 | — | — | WO | disclosed |
| EP-2147913-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-01-27 | — | — | EP | disclosed |