SCHEMBL323453

SCHEMBL323453

O=C(O)C=C(CC(=O)OC(=O)/C=C\C(=O)OC(=O)CC(=CC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
TSHR P16473 1/20 0.54
HCAR2 Q8TDS4 4/20 0.35
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1289878 0.87 KDM4E (0.62) KDM4ETSHR
SCHEMBL11868324 0.85 KDM4E (0.43) KDM4ETSHR
SCHEMBL28807064 0.85 TSHR (0.50) KDM4ETSHR
SCHEMBL11856751 0.80 KDM4E (0.54) KDM4ETSHR
SCHEMBL8650644 0.79 KDM4E (0.44) KDM4ETSHR
SCHEMBL28692168 0.78 TSHR (0.47) KDM4ETSHR
SCHEMBL28942452 0.78 TSHR (0.83) KDM4ETSHR
SCHEMBL6400546 0.77 KDM4E (0.50) KDM4ETSHR
SCHEMBL10259507 0.77 TSHR (0.60) KDM4ETSHRHCAR2
SCHEMBL15741505 0.77 TSHR (0.60) KDM4ETSHRHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2591027-B1 STRUCTURED ACRYLATE COPOLYMER THICKENERS LUBRIZOL ADVANCED MAT INC (US) 2015-09-23 EP claimed
US-8673277-B2 Structured acrylate copolymer thickeners LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-03-18 US claimed
EP-2591027-A1 STRUCTURED ACRYLATE COPOLYMER THICKENERS Lubrizol Advanced Materials, Inc. (US) 2013-05-15 EP claimed
US-20130115185-A1 Structured Acrylate Copolymer Thickeners LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-05-09 US claimed
WO-2012006402-A1 STRUCTURED ACRYLATE COPOLYMER THICKENERS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-01-12 WO claimed
EP-2591027-B1 STRUCTURED ACRYLATE COPOLYMER THICKENERS LUBRIZOL ADVANCED MAT INC (US) 2015-09-23 EP disclosed
EP-0591445-B1 LIQUID DETERGENT WITH STABILIZED ENZYME GENENCOR INT (US) 1999-08-18 EP disclosed
EP-0591445-A1 LIQUID DETERGENT WITH STABILIZED ENZYME GENENCOR INTERNATIONAL, INC. (US) 1994-04-13 EP disclosed
WO-1993000418-A1 LIQUID DETERGENT WITH STABILIZED ENZYME GENENCOR INTERNATIONAL, INC. (US) 1993-01-07 WO disclosed
EP-0482417-A1 Emulsion composition comprising a high molecular weight anionic emulsifying agent and a low molecular weight cationic surfactant, and methods relating thereto THE B.F. GOODRICH COMPANY (US) 1992-04-29 EP disclosed
EP-0459373-A2 Bioadhesive carboxylic polymer composition and method relating thereto THE B.F. GOODRICH COMPANY (US) 1991-12-04 EP disclosed
US-5039446-A Bound to enzyme inhibitor GENENCOR INTERNATIONAL, INC. (US) 1991-08-13 US disclosed