Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.83 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aconitic Acid SCHEMBL2022211 | 0.91 | TSHR (1.00) | TSHRKDM4EGABRR1GABRR2BLM | |
| Aconitic Acid SCHEMBL16935 | 0.91 | TSHR (1.00) | TSHRKDM4EGABRR1GABRR2BLM | |
| Aconitic Acid SCHEMBL1289876 | 0.91 | TSHR (1.00) | TSHRKDM4EGABRR1GABRR2BLM | |
| Aconitic Acid SCHEMBL1275978 | 0.91 | TSHR (1.00) | TSHRKDM4EGABRR1GABRR2BLM | |
| Aconitic Acid SCHEMBL22334 | 0.91 | TSHR (1.00) | TSHRKDM4EGABRR1GABRR2BLM | |
| Aconitic Acid SCHEMBL219037 | 0.91 | TSHR (1.00) | TSHRKDM4EGABRR1GABRR2BLM | |
| Aconitic Acid SCHEMBL9394649 | 0.89 | TSHR (0.95) | TSHRKDM4EALOX15HSD17B10ABAT | |
| SCHEMBL19386129 | 0.89 | KDM4E (0.68) | TSHRKDM4EALOX15HSD17B10ABAT | |
| Aconitic Acid SCHEMBL31158182 | 0.89 | TSHR (0.95) | TSHRKDM4EALOX15HSD17B10ABAT | |
| Aconitic Acid SCHEMBL29245498 | 0.89 | TSHR (0.95) | TSHRKDM4EALOX15HSD17B10ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384374-A | Preparation method of FTEP-TBFc compound and application thereof in resisting tumors | 南华大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-115490672-A | Photosensitizer with photothermal and photodynamic effects and preparation method and application thereof | 南华大学 | 2022-12-20 | — | — | CN | disclosed |