Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 3/20 | 0.43 |
| ▸ | LPL | P06858 | 7/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980653 | 0.84 | LIPG (0.41) | LIPGCA1CA2LPLTRPV1 | |
| SCHEMBL30044969 | 0.83 | TYR (0.50) | LIPGCA1CA2TYRHTT | |
| SCHEMBL4633219 | 0.83 | TYR (0.50) | LIPGCA1CA2TYRHTT | |
| SCHEMBL1133572 | 0.77 | TYR (0.53) | LIPGTYRHTTMEN1TP53 | |
| SCHEMBL31230428 | 0.77 | TYR (0.53) | LIPGTYRHTTMEN1TP53 | |
| SCHEMBL11711991 | 0.77 | LIPG (0.74) | LIPGTYRLPLTRPV1MGLL | |
| SCHEMBL167918 | 0.76 | TYR (0.55) | TYRHTTNPC1HPGDMAPK1 | |
| Ammonia Solution, Strong SCHEMBL2921373 | 0.76 | TYR (0.46) | LIPGCA1CA2TYRHTT | |
| SCHEMBL28916682 | 0.76 | TYR (0.41) | TYRHTTNPC1HPGDMAPK1 | |
| SCHEMBL3140999 | 0.76 | LIPG (0.49) | LIPGCA1CA2TYRLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018547-A1 | AMINOQUINOLINE COMPOUNDS | PFIZER INC. (US) | 2010-02-18 | — | — | WO | disclosed |