Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231832 | 0.88 | HSD11B1 (0.73) | HSD11B1HSD11B2 | |
| SCHEMBL3230804 | 0.86 | HSD11B1 (0.71) | HSD11B1HSD11B2 | |
| SCHEMBL7945284 | 0.86 | HSD11B1 (0.76) | HSD11B1HSD11B2 | |
| SCHEMBL3232716 | 0.85 | HSD11B1 (0.69) | HSD11B1HSD11B2 | |
| SCHEMBL3232705 | 0.85 | HSD11B1 (0.69) | HSD11B1HSD11B2 | |
| SCHEMBL13784342 | 0.84 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL3227133 | 0.84 | HSD11B1 (0.72) | HSD11B1HSD11B2 | |
| SCHEMBL3231636 | 0.83 | HSD11B1 (0.76) | HSD11B1HSD11B2 | |
| SCHEMBL3237810 | 0.82 | HSD11B1 (0.68) | HSD11B1HSD11B2 | |
| SCHEMBL4331939 | 0.82 | HSD11B1 (1.00) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011917-A1 | SEH AND 11β-HSD1 DUAL INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010011917-A1 | SEH AND 11β-HSD1 DUAL INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-01-28 | — | — | WO | disclosed |