Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 6/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.31 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2237905 | 0.94 | CHRNB4 (0.39) | CHRNB4CHRNA3DRD2DRD3SMN1; SMN2 | |
| SCHEMBL12346740 | 0.90 | CHRNB4 (0.42) | CHRNB4CHRNA3DRD2DRD3SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL2239467 | 0.88 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL12346741 | 0.83 | BDKRB1 (0.53) | BDKRB1DRD2 | |
| Trifluoroacetic Acid SCHEMBL2237661 | 0.83 | KDM4E (0.44) | TDP1USP2MAPT | |
| Trifluoroacetic Acid SCHEMBL2242040 | 0.82 | BDKRB1 (0.40) | BDKRB1DRD2CYP2D6TDP1MAPT | |
| SCHEMBL2237908 | 0.81 | TDP1 (0.34) | BDKRB1DRD2DRD3HPGDCYP1A2 | |
| Trifluoroacetic Acid SCHEMBL2239201 | 0.81 | THRB (0.40) | BDKRB1DRD2DRD3CYP3A4CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL2243351 | 0.80 | BDKRB1 (0.39) | BDKRB1DRD2TDP1MAPT | |
| Trifluoroacetic Acid SCHEMBL2237417 | 0.80 | BDKRB1 (0.38) | BDKRB1CYP3A4TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020556-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2010-02-25 | — | — | WO | claimed |