Chloroform

Chloroform

SCHEMBL3237209

CNC.ClC(Cl)Cl

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL7893155 0.88
Dimethylamine SCHEMBL28098217 0.88 ALDH1A1 (0.56)
Dimethylamine SCHEMBL9854037 0.88 ALDH1A1 (0.56)
Dimethylamine SCHEMBL27962927 0.82
Dimethylamine SCHEMBL10821635 0.82
Chloroform SCHEMBL27291458 0.72
Dimethylamine SCHEMBL4910341 0.72
Chloroform SCHEMBL3164509 0.72
Dimethylamine SCHEMBL28874924 0.72
Dimethylamine SCHEMBL1030 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269744-A Methods for preparing Toll-like receptor modulator compounds 吉利德科学公司 2022-04-01 CN claimed
CN-113480546-A Preparation of Baricitinib and derivatives thereof 江苏君若药业有限公司 2021-10-08 CN claimed
CN-111433189-A Process for producing 11- β -hydroxysteroid dehydrogenase type 1 inhibitor 帝斯曼知识产权资产管理有限公司 2020-07-17 CN claimed
EP-1235792-A4 PREPARATION OF [4S-(4ALPHA,7ALPHA,10ABETA)]-4-AMINO-OCTAHYDRO-5-OXO-7H-PYRIDO 2,1-B] 1,3]THIAZEPINE-7-CARBOXYLIC ACID, METHYL ESTER AND SALTS THEREOF VIA NOVEL DISULFIDES BRISTOL MYERS SQUIBB CO (US) 2003-06-25 EP claimed
EP-1235792-A1 PREPARATION OF [4S-(4ALPHA,7ALPHA,10ABETA)]-4-AMINO-OCTAHYDRO-5-OXO-7H-PYRIDO 2,1-B] 1,3]THIAZEPINE-7-CARBOXYLIC ACID, METHYL ESTER AND SALTS THEREOF VIA NOVEL DISULFIDES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-09-04 EP claimed
WO-2002042258-A1 PREPARATION OF [4S-(4α,7α,10Aβ)]-4-AMINO-OCTAHYDRO-5-OXO-7H-PYRIDO[2,1-B][1,3]THIAZEPINE-7-CARBOXYLIC ACID, METHYL ESTER AND SALTS THEREOF VIA NOVEL DISULFIDES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-05-30 WO claimed
US-6162913-A Preparation of [4S-(4α,7α,10aβ)]-4-amino-octahydro-5-oxo-7H-pyrido[2,1 -b] [1,3]thiazepine-7-carboxylic acid, methyl ester and salts thereof via novel disulfides BRISTOL-MYERS SQUIBB CO. (US) 2000-12-19 US claimed
EP-0157151-A1 New process for preparing cis-3,3,5-trimethylcyclohexyl-D,L-alpha-(3-pyridinecarboxy)-phenylacetate RAVIZZA S.p.A. (IT) 1985-10-09 EP claimed
EP-4334404-B1 PRETREATMENT FORMULATIONS FOR DIGITAL PRINTING NUR INK INNOVATIONS LTD (IL) 2025-06-04 EP disclosed
WO-2025073221-A1 ANILINOPYRIMIDO HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 中国药科大学 2025-04-10 WO disclosed
CN-115873000-B Isoquinolinones and quinazolinones compounds, and composition and application thereof 中山医诺维申新药研发有限公司 2025-02-28 CN disclosed
CN-119390681-A Process for preparing COT inhibitor compounds 吉利德科学公司 2025-02-07 CN disclosed
WO-2025021158-A1 SPIROCYCLICALKENYL OR AZAALKENYL COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF 上海美悦生物科技发展有限公司 2025-01-30 WO disclosed
CN-115397824-B Process for preparing COT inhibitor compounds 吉利德科学公司 2024-10-22 CN disclosed
US-4237305-A INTERMEDIATES FOR PREPARING NEW ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-02 US disclosed
US-4234724-A OXADETHIACEPHEMCARBOXYLIC ACIDS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-11-18 US disclosed
EP-0013762-A2 Cephem and cepham compounds, processes for their preparation, pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-08-06 EP disclosed
EP-0007470-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-02-06 EP disclosed
EP-0004570-A1 Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1979-10-17 EP disclosed
US-4166115-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-08-28 US disclosed