⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547941 | 0.82 | CES2 (0.62) | — | |
| SCHEMBL143645 | 0.80 | — | — | |
| SCHEMBL9432069 | 0.80 | — | — | |
| SCHEMBL11198155 | 0.77 | CES2 (0.50) | — | |
| SCHEMBL11198165 | 0.77 | CES2 (0.50) | — | |
| SCHEMBL11345781 | 0.76 | CES2 (0.55) | — | |
| SCHEMBL11345762 | 0.76 | CES2 (0.55) | — | |
| SCHEMBL17303312 | 0.75 | CES2 (0.54) | — | |
| Thiophene Carboxylic Acid SCHEMBL2355560 | 0.75 | DAO (0.76) | — | |
| Thiophene Carboxylic Acid SCHEMBL30775706 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453969-A | Thienylglyoxylonitrile oximino phenylcarbamates for the protection of crops against injury by herbicides | CIBA-GEIGY CORPORATION (US) | 1984-06-12 | — | — | US | claimed |
| US-4234737-A | Process for preparing thienylglyoxylic acids and amides | STAUFFER CHEMICAL COMPANY (US) | 1980-11-18 | — | — | US | claimed |
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0707578-A1 | 2-OXIMINO-2-THIENYL-ACETIC ACID DERIVATIVES | BAYER AG (DE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001973-A1 | 2-OXIMINO-2-THIENYL-ACETIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-19 | — | — | WO | disclosed |
| US-4453969-A | Thienylglyoxylonitrile oximino phenylcarbamates for the protection of crops against injury by herbicides | CIBA-GEIGY CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4234737-A | Process for preparing thienylglyoxylic acids and amides | STAUFFER CHEMICAL COMPANY (US) | 1980-11-18 | — | — | US | disclosed |