Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990105 | 1.00 | KMT2A (0.45) | KMT2AMEN1MMP1MMP2MMP9 | |
| SCHEMBL323735 | 1.00 | KMT2A (0.45) | KMT2AMEN1MMP1MMP2MMP9 | |
| SCHEMBL29364700 | 1.00 | KMT2A (0.45) | KMT2AMEN1MMP1MMP2MMP9 | |
| SCHEMBL2081536 | 0.85 | KMT2A (0.47) | KMT2AMEN1CA1CA2LMNA | |
| SCHEMBL7587366 | 0.85 | KMT2A (0.47) | KMT2AMEN1CA1CA2LMNA | |
| SCHEMBL10254866 | 0.85 | KMT2A (0.44) | KMT2AMEN1MMP1MMP2MMP9 | |
| SCHEMBL2325747 | 0.85 | KMT2A (0.47) | KMT2AMEN1CA1CA2LMNA | |
| SCHEMBL3089042 | 0.85 | KMT2A (0.49) | KMT2AMEN1LMNAGAASTAT3 | |
| SCHEMBL10012108 | 0.85 | KMT2A (0.46) | KMT2AMEN1MMP1MMP2MMP9 | |
| SCHEMBL10012543 | 0.85 | KMT2A (0.48) | KMT2AMEN1CA2LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865833-A | metalaxyl-M and synthesis method thereof | 浙江禾本科技股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114591261-A | Synthesis method of chiral benzyl carboxylate compound | 上海药坦药物研究开发有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108623455-B | Intermediate of anti-heart failure medicine | 成都博腾药业有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113979907-A | Cyclohexane-1, 3-dione compound and application thereof | 郑州恒诚仪器耗材有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111205208-B | Cyclohexane-1, 3-diketone compound and synthetic method and application thereof | 郑州恒诚仪器耗材有限公司 | 2021-12-17 | — | — | CN | disclosed |
| WO-2021143617-A1 | CYCLOHEXADIENE OXIME ETHER COMPOUND, SYNTHESIS METHOD THEREFOR AND APPLICATION THEREOF | 郑州手性药物研究院有限公司 | 2021-07-22 | — | — | WO | disclosed |
| CN-112409378-A | Tricyclic PI3K inhibitor compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-108349996-B | Tricyclic PI3K inhibitor compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-107174584-B | Application of piperazine structure-containing compound in preparation of LSD1 inhibitor | 福建金乐医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |
| EP-3347361-B1 | TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2020-08-05 | — | — | EP | disclosed |
| WO-1992018467-A1 | CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |
| EP-0308755-B1 | DERIVATIVES OF 7-(HETERO)ARYLOXY-NAPHTHALEN-2-YLOXY)ALCANOIC ACID | BAYER AG (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0315008-B1 | DERIVATIVES OF (6-(HETERO)ARYLOXY-NAPHTHALIN-2-YL-OXY)ALCANOIC ACID | BAYER AG (DE) | 1992-09-09 | — | — | EP | disclosed |
| EP-0453842-A2 | Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |
| EP-0309864-B1 | ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-PROPIONIC-ACID DERIVATIVES | BAYER AG (DE) | 1991-05-22 | — | — | EP | disclosed |
| EP-0347679-A1 | 1,7-Dioxynaphthalene derivatives | BAYER AG (DE) | 1989-12-27 | — | — | EP | disclosed |
| EP-0342440-A1 | Halogen-substituted phenoxybenzyl-(thi)ol derivatives | BAYER AG (DE) | 1989-11-23 | — | — | EP | disclosed |
| EP-0315008-A2 | Derivatives of (6-(hetero)aryloxy-naphthalin-2-yl-oxy)alcanoic acid | BAYER AG (DE) | 1989-05-10 | — | — | EP | disclosed |
| EP-0308755-A2 | Derivatives of 7-(hetero)aryloxy-naphthalen-2-yloxy)alcanoic acid | BAYER AG (DE) | 1989-03-29 | — | — | EP | disclosed |
| US-4629493-A | NONPHYTOTOXIC TO BROAD LEAF PLANTS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-12-16 | — | — | US | disclosed |