Sugi Predict

Sugi Predict / Compounds / SCHEMBL323735

SCHEMBL323735

SCHEMBL323735

COC(=O)[C@H](C)OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ MMP1 P03956 2/20 0.42
▸ MMP2 P08253 2/20 0.42
▸ MMP9 P14780 2/20 0.42
▸ MMP13 P45452 2/20 0.42
▸ CA1 P00915 2/20 0.42
▸ CA2 P00918 2/20 0.42
▸ MMP8 P22894 1/20 0.42
▸ F2 P00734 1/20 0.41
▸ PRSS1 P07477 1/20 0.41
▸ PRSS2 P07478 1/20 0.41
▸ PRSS3 P35030 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ GAA P10253 3/20 0.41
▸ MMP3 P08254 1/20 0.40
▸ MMP7 P09237 1/20 0.40
▸ STAT3 P40763 1/20 0.40
▸ CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1990105 1.00 KMT2A (0.45) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL323736 1.00 KMT2A (0.45) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL29364700 1.00 KMT2A (0.45) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL2081536 0.85 KMT2A (0.47) KMT2AMEN1CA1CA2LMNA
SCHEMBL7587366 0.85 KMT2A (0.47) KMT2AMEN1CA1CA2LMNA
SCHEMBL10254866 0.85 KMT2A (0.44) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL2325747 0.85 KMT2A (0.47) KMT2AMEN1CA1CA2LMNA
SCHEMBL3089042 0.85 KMT2A (0.49) KMT2AMEN1LMNAGAASTAT3
SCHEMBL10012108 0.85 KMT2A (0.46) KMT2AMEN1MMP1MMP2MMP9
SCHEMBL10012543 0.85 KMT2A (0.48) KMT2AMEN1CA2LMNACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084044-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS ENKO CHEM, INC. (US) 2025-03-13 — — US disclosed
EP-4462999-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS Enko Chem, Inc. (US) 2024-11-20 — — EP disclosed
CN-117865833-A metalaxyl-M and synthesis method thereof 浙江禾本科技股份有限公司 2024-04-12 — — CN disclosed
CN-117865833-A metalaxyl-M and synthesis method thereof 浙江禾本科技股份有限公司 2024-04-12 — — CN disclosed
CN-116888094-A Method for preparing D-alanine alkyl ester, derivative thereof, and pharmaceutical or agricultural product comprising same 株式会社LG化学 2023-10-13 — — CN disclosed
CN-116829531-A Method for preparing N-acyl derivative, composition and medicine or agricultural product containing the same 株式会社LG化学 2023-09-29 — — CN disclosed
WO-2023137307-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS ENKO CHEM, INC. (US) 2023-07-20 — — WO disclosed
CN-116171269-A Process for preparing D-alanine alkyl ester 株式会社LG化学 2023-05-26 — — CN disclosed
WO-2023277587-A1 METHOD FOR PREPARING N-ACYL DERIVATIVE, COMPOSITION, AND PHARMACEUTICAL OR AGRICULTURAL PRODUCT CONTAINING SAME 주식회사 엘지화학 2023-01-05 — — WO disclosed
WO-2023277590-A1 METHOD FOR PREPARING ALKYL-D-ALANINATE, ALKYL-D-ALANINATE, ALKYL-D-ALANINATE DERIVATIVE, AND PHARMACEUTICAL OR AGRICULTURAL PRODUCT INCLUDING SAME 주식회사 엘지화학 2023-01-05 — — WO disclosed
WO-2009010478-A2 USE OF PIPERIDINE DERIVATIVES AS AGONISTS OF CHEMOKINE RECEPTOR ACTIVITY EUROSCREEN S.A. (BE) 2009-01-22 — — WO disclosed
US-20080132480-A1 Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease ASTRAZENECA AB (SE) 2008-06-05 — — US disclosed
EP-1155616-B1 Process for the preparation of (N-phenylacetyl-N-2,6-xylil)methyl alaninate ISAGRO SPA (IT) 2003-01-29 — — EP disclosed
EP-0946093-B1 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO SPA (IT) 2002-08-28 — — EP disclosed
EP-1155616-A1 Process for the preparation of (N-phenylacetyl-N-2,6-xylil)methyl alaninate ISAGRO S.p.A. (IT) 2001-11-21 — — EP disclosed
US-6228885-B1 Fungicidal compositions based on (N-phenylacetyl-N-2,6-XYLYL)methyl alaninate ISAGRO S.P.A. (IT) 2001-05-08 — — US disclosed
EP-0946093-A2 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO S.p.A. (IT) 1999-10-06 — — EP disclosed
WO-1998026654-A2 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO S.P.A. (IT) 1998-06-25 — — WO disclosed
EP-0442172-A1 Oxime derivatives and Herbicides containing the same as an active ingredient TEIJIN LIMITED (JP) 1991-08-21 — — EP disclosed
EP-0221516-A1 7-(Aryloxy)-2-quinolyloxy-alkane-acid derivatives, process for their preparation and herbicides containing them SCHERING AKTIENGESELLSCHAFT (DE) 1987-05-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084044-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS PPOX, CYP4X1, PNPO KMT2A 4160/4885MEN1 4497/4885MMP1 1614/4885
US-20080132480-A1 Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease CYP26A1, CYP1A1, GPBAR1 KMT2A 1697/4885MEN1 4025/4885MMP1 1592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.