⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879803 | 0.75 | — | — | |
| SCHEMBL8044195 | 0.73 | — | — | |
| SCHEMBL22551299 | 0.72 | CYP2C19 (0.60) | — | |
| SCHEMBL6444227 | 0.72 | — | — | |
| SCHEMBL1885262 | 0.71 | — | — | |
| SCHEMBL18487168 | 0.71 | CYP2C19 (0.40) | — | |
| SCHEMBL2289375 | 0.69 | — | — | |
| SCHEMBL10403366 | 0.69 | — | — | |
| SCHEMBL15791167 | 0.69 | — | — | |
| SCHEMBL10403365 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916963-A | Multivalent ligand clusters with diamine scaffolds for targeted delivery of therapeutic agents | 上海舶望制药有限公司 | 2023-10-20 | — | — | CN | claimed |
| US-11597926-B2 | Thiophosphoramidites | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-03-07 | — | — | US | claimed |
| CN-114206389-A | Multivalent ligand clusters for targeted delivery of therapeutic agents | 有丝分裂疗法有限责任公司 | 2022-03-18 | — | — | CN | claimed |
| EP-3923989-A1 | MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | Mitotherapeutix LLC (US) | 2021-12-22 | — | — | EP | claimed |
| US-20210115438-A1 | NOVEL THIOPHOSPHORAMIDITES | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2021-04-22 | — | — | US | claimed |
| EP-3728590-A1 | NOVEL THIOPHOSPHORAMIDITES | Roche Innovation Center Copenhagen A/S (DK) | 2020-10-28 | — | — | EP | claimed |
| WO-2020191183-A1 | MULTIVALENT LIGAND CLUSTERS FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS | MITOTHERAPEUTIX LLC (US) | 2020-09-24 | — | — | WO | claimed |
| CN-111448316-A | Novel thiophosphorous acid amides | 罗氏创新中心哥本哈根有限公司 | 2020-07-24 | — | — | CN | claimed |
| EP-3484908-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM Chemicals Llc (US) | 2019-05-22 | — | — | EP | claimed |
| US-20180125986-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | SATYAM APPARAO (IN) | 2018-05-10 | — | — | US | claimed |
| US-4235920-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | claimed |
| US-4235917-A | N-Alkyl-N-acyl derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | claimed |
| US-4232030-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-11-04 | — | — | US | claimed |
| US-4196211-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1980-04-01 | — | — | US | claimed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | claimed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | claimed |
| US-4078068-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | claimed |
| US-4078067-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | claimed |
| US-4076826-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1978-02-28 | — | — | US | claimed |