Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394776 | 0.89 | KMT2A (0.60) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL13447836 | 0.85 | KMT2A (0.57) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL3232890 | 0.80 | MEN1 (0.44) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL3232537 | 0.79 | MAPT (0.43) | KMT2AMEN1TDP1HTR3EHTR3B | |
| SCHEMBL2172544 | 0.76 | MEN1 (0.51) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL12394779 | 0.74 | MEN1 (0.76) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL3232475 | 0.74 | MEN1 (0.41) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL10364639 | 0.74 | MEN1 (0.57) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL2172173 | 0.74 | KDM4E (0.52) | KMT2AMEN1TDP1POLBHSP90AA1 | |
| SCHEMBL3232870 | 0.72 | SMN1; SMN2 (0.45) | KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029065-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |