Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 13/20 | 0.72 |
| ▸ | F2 | P00734 | 6/20 | 0.72 |
| ▸ | KLK1 | P06870 | 4/20 | 0.72 |
| ▸ | TMPRSS15 | P98073 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240254 | 0.92 | PRSS1 (0.79) | PRSS1F2KLK1TMPRSS15KDM4E | |
| SCHEMBL3243442 | 0.85 | PRSS1 (0.73) | PRSS1F2KLK1TMPRSS15KDM4E | |
| SCHEMBL3245051 | 0.84 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15KDM4E | |
| SCHEMBL7311244 | 0.84 | PRSS1 (1.00) | PRSS1F2KLK1TMPRSS15KDM4E | |
| SCHEMBL3240107 | 0.84 | PRSS1 (0.82) | PRSS1F2KLK1TMPRSS15KDM4E | |
| SCHEMBL13431862 | 0.83 | PRSS1 (0.82) | PRSS1F2KLK1TMPRSS15KDM4E | |
| Acetic Acid SCHEMBL7312877 | 0.82 | PRSS1 (0.96) | PRSS1F2KLK1TMPRSS15KDM4E | |
| SCHEMBL3245689 | 0.82 | PRSS1 (0.83) | PRSS1F2KLK1TMPRSS15KDM4E | |
| Acetic Acid SCHEMBL7311943 | 0.82 | PRSS1 (0.96) | PRSS1F2KLK1TMPRSS15KDM4E | |
| SCHEMBL3238583 | 0.82 | PRSS1 (0.79) | PRSS1F2KLK1TMPRSS15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671057-B2 | Therapeutic agent for type II diabetes comprising protease-inhibiting compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20080009537-A1 | Therapeutic Agent for Diabetes Comprising Protease-Inhibiting Compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009537-A1 | Therapeutic Agent for Diabetes Comprising Protease-Inhibiting Compound | DPP4, IAPP, DPP7 | PRSS1 25/4885F2 805/4885KLK1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.