Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191857 | 0.75 | ESR1 (0.42) | MAPTKMT2ACHRM2CHRM3KIF11 | |
| SCHEMBL17968475 | 0.74 | MAPT (0.46) | MAPTKMT2AKCNN4HTTPARP10 | |
| SCHEMBL28147152 | 0.72 | CYP2C19 (0.47) | KCNN4ALOX15PPARGPPARA | |
| SCHEMBL27602772 | 0.71 | MAPT (0.50) | MAPTKMT2AKCNN4HTTCHRM2 | |
| SCHEMBL1170319 | 0.71 | PARP10 (0.42) | MAPTKMT2AKCNN4PARP10EPHX1 | |
| SCHEMBL27757832 | 0.70 | MAPT (0.55) | MAPTKMT2AKCNN4HTTPARP10 | |
| SCHEMBL7924474 | 0.70 | CES1 (0.44) | MAPTKMT2AKCNN4ALOX15 | |
| SCHEMBL20773030 | 0.70 | KIF11 (0.40) | MAPTKMT2AKIF11 | |
| SCHEMBL22187026 | 0.70 | KIF11 (0.44) | MAPTEPHX1KIF11 | |
| SCHEMBL26135574 | 0.70 | CYP2C19 (0.44) | KCNN4ALOX15PPARGPPARAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045580-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | EXELIXIS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |