Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3244696 | 0.92 | F10 (0.45) | F10ABCB11F2ST14PTGS2 | |
| Hydrochloric Acid SCHEMBL3245423 | 0.91 | F10 (0.44) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL3244221 | 0.90 | F10 (0.44) | F10 | |
| SCHEMBL3510008 | 0.87 | F10 (0.65) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL3246184 | 0.81 | F10 (0.38) | F10F2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL8230562 | 0.80 | F10 (0.60) | F10ABCB11F2ST14PTGS2 | |
| Hydrochloric Acid SCHEMBL3506415 | 0.79 | F10 (0.59) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL8225130 | 0.79 | F10 (0.59) | F10ABCB11F2ST14PTGS2 | |
| Hydrochloric Acid SCHEMBL3507990 | 0.79 | F10 (0.58) | F10ABCB11F2ST14PTGS2 | |
| SCHEMBL3508052 | 0.77 | F10 (0.55) | F10ABCB11F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029546-B1 | ARYL-SUBSTITUTED HETEROCYCLES, AND USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2010-07-28 | — | — | EP | disclosed |