Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3244696 | 0.88 | F10 (0.45) | F10F2 | |
| SCHEMBL3507150 | 0.87 | F10 (0.49) | F10F2MAPT | |
| SCHEMBL3238076 | 0.81 | F10 (0.49) | F10F2ALDH1A1HSD17B10TSHR | |
| SCHEMBL8225098 | 0.80 | F10 (0.50) | F10F2MAPTALDH1A1KMT2A | |
| SCHEMBL3244205 | 0.79 | F10 (0.41) | F10F2ALDH1A1DGAT2KDM4E | |
| Hydrochloric Acid SCHEMBL3245423 | 0.79 | F10 (0.44) | F10F2SMN1; SMN2 | |
| SCHEMBL8225103 | 0.78 | F10 (0.47) | F10F2DGAT2 | |
| Hydrochloric Acid SCHEMBL3262758 | 0.78 | DGAT2 (0.40) | F10F2MAPTHPGDDGAT2 | |
| Hydrochloric Acid SCHEMBL3508737 | 0.78 | F10 (0.46) | F10F2DGAT2 | |
| SCHEMBL8230562 | 0.75 | F10 (0.60) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029546-B1 | ARYL-SUBSTITUTED HETEROCYCLES, AND USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2010-07-28 | — | — | EP | disclosed |