Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.53 |
| ▸ | KLK1 | P06870 | 4/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617141 | 0.90 | TRPM8 (0.46) | F2PRSS1KLK1TRPM8MAPT | |
| SCHEMBL7617144 | 0.90 | TRPM8 (0.46) | F2PRSS1KLK1TRPM8MAPT | |
| Hydrochloric Acid SCHEMBL7616006 | 0.89 | TRPM8 (0.45) | F2PRSS1KLK1TRPM8MAPT | |
| Hydrochloric Acid SCHEMBL7616011 | 0.89 | TRPM8 (0.45) | F2PRSS1KLK1TRPM8MAPT | |
| SCHEMBL7523243 | 0.87 | F2 (0.47) | F2PRSS1KLK1TRPM8MAPT | |
| SCHEMBL3243842 | 0.87 | PRSS1 (0.53) | F2PRSS1KLK1MAPTKMT2A | |
| SCHEMBL7192286 | 0.87 | F2 (0.47) | F2PRSS1KLK1TRPM8MAPT | |
| SCHEMBL3243839 | 0.87 | PRSS1 (0.53) | F2PRSS1KLK1MAPTKMT2A | |
| SCHEMBL3232966 | 0.86 | PRSS1 (0.53) | F2PRSS1KLK1MAPTKMT2A | |
| SCHEMBL7303571 | 0.84 | PRSS1 (0.69) | F2PRSS1KLK1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671057-B2 | Therapeutic agent for type II diabetes comprising protease-inhibiting compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-02 | — | — | US | disclosed |
| US-20080009537-A1 | Therapeutic Agent for Diabetes Comprising Protease-Inhibiting Compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009537-A1 | Therapeutic Agent for Diabetes Comprising Protease-Inhibiting Compound | DPP4, IAPP, DPP7 | F2 805/4885PRSS1 25/4885KLK1 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.