SCHEMBL323859

SCHEMBL323859

C[C@H]1NCCNC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254694 1.00
SCHEMBL325884 1.00
SCHEMBL8272813 0.85
SCHEMBL7812982 0.85
SCHEMBL7810948 0.85
Hydrochloric Acid SCHEMBL3841841 0.83 SLC6A2 (0.37)
Tert-Butyl Formate SCHEMBL27783529 0.80 TDP1 (0.43)
SCHEMBL13165096 0.78 CTSD (0.36)
SCHEMBL13165136 0.78 CTSD (0.36)
SCHEMBL13112921 0.78 CTSD (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119040410-A Preparation method of (R) -4- (4-fluorobenzoyl) -3-methylpiperazine-2-one 成都科圣原医药科技有限公司 2024-11-29 CN claimed
CN-117551104-A New preparation method of female hectic fever treatment medicine 北京康立生医药技术开发有限公司 2024-02-13 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
US-20260049074-A1 THIADIAZOLYL DERIVATIVES IDEAYA BIOSCIENCES, INC. (US) 2026-02-19 US disclosed
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 EP disclosed
WO-2026016156-A1 SYNTHESIS METHOD FOR FEZOLINETANT AND SERIES OF INTERMEDIATE COMPOUNDS THEREOF 杭州科巢生物科技有限公司 2026-01-22 WO disclosed
US-12509454-B2 Thiadiazolyl derivatives IDEAYA BIOSCIENCES, INC. (US) 2025-12-30 US disclosed
EP-4630410-A1 POLQ INHIBITORS Astrazeneca AB (SE) 2025-10-15 EP disclosed
US-12414954-B2 POLQ inhibitors ASTRAZENECA AB (SE) 2025-09-16 US disclosed
WO-2025153996-A3 PROCESSES FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED R-FEZOLINETANT ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2025-08-28 WO disclosed
US-20250195530-A1 POLQ INHIBITORS ASTRAZENECA AB (SE) 2025-06-19 US disclosed
WO-2013050424-A1 NOVEL CHIRAL N-ACYL-5,6,7,(8-SUBSTITUTED)-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR MEDIATED DISORDERS AND CHIRAL SYNTHESIS THEREOF EUROSCREEN S.A. (BE) 2013-04-11 WO disclosed
US-8389526-B2 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives NOVARTIS AG (CH) 2013-03-05 US disclosed
WO-2013007371-A2 KINETIC RESOLUTION OF CHIRAL AMINES ETH ZURICH (CH) 2013-01-17 WO disclosed
WO-2013007371-A2 KINETIC RESOLUTION OF CHIRAL AMINES ETH ZURICH (CH) 2013-01-17 WO disclosed
EP-2462143-A1 3-HETEROARYLMETHYL-IMIDAZO[1,2-B]PYRIDAZIN-6-YL DERIVATIVES AS C-MET TYROSINE KINASE MODULATORS Novartis AG (CH) 2012-06-13 EP disclosed
WO-2012004604-A1 TETRAZOLE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS Convergence Pharmaceuticals Limited (GB) 2012-01-12 WO disclosed
US-20110039831-A1 3-HETEROARYLMETHYL-IMIDAZO[1,2-B]PYRIDAZIN-6-YL DERIVATIVES NOVARTIS AG (CH) 2011-02-17 US disclosed
WO-2011015652-A1 3-HETEROARYLMETHYL-IMIDAZO[1,2-B]PYRIDAZIN-6-YL DERIVATIVES AS C-MET TYROSINE KINASE MODULATORS NOVARTIS AG (CH) 2011-02-10 WO disclosed