Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSGALNACT1 | Q8TDX6 | 5/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293676 | 1.00 | CSGALNACT1 (0.49) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2293683 | 1.00 | CSGALNACT1 (0.49) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2293690 | 1.00 | CSGALNACT1 (0.49) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2299974 | 0.94 | DGAT1 (0.45) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2299985 | 0.94 | DGAT1 (0.45) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2299980 | 0.94 | DGAT1 (0.45) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL3230912 | 0.94 | DGAT1 (0.45) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2301923 | 0.93 | DGAT1 (0.42) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2301905 | 0.93 | DGAT1 (0.42) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2301911 | 0.93 | DGAT1 (0.42) | CSGALNACT1DGAT1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | claimed |
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |