Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.74 |
| ▸ | DRD2 | P14416 | 3/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.74 |
| ▸ | HTR7 | P34969 | 1/20 | 0.74 |
| ▸ | HTR6 | P50406 | 1/20 | 0.74 |
| ▸ | DRD4 | P21917 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 3/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514768 | 0.89 | DRD2 (0.73) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL1727871 | 0.86 | DRD2 (0.71) | HTR2ADRD2HTR1AHTR7DRD4 | |
| SCHEMBL13946744 | 0.84 | DRD2 (0.79) | DRD2DRD4ADRA1ADRD3MAPT | |
| Hydrochloric Acid SCHEMBL3434997 | 0.84 | KCNH2 (0.72) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL30767216 | 0.83 | KCNH2 (0.90) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL2213204 | 0.83 | HTR2A (0.62) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL8477588 | 0.83 | KCNH2 (0.74) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL12441084 | 0.83 | KCNH2 (0.74) | HTR2ADRD2HTR1AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7658247 | 0.82 | KCNH2 (0.88) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL4525555 | 0.82 | KCNH2 (1.00) | HTR2ADRD2HTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038948-A2 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS | GREEN CROSS CORPORATION (KR) | 2010-04-08 | — | — | WO | disclosed |