⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129975 | 0.77 | TSHR (0.61) | — | |
| SCHEMBL713815 | 0.77 | — | — | |
| SCHEMBL28140 | 0.77 | — | — | |
| Formaldehyde SCHEMBL10275626 | 0.75 | ALDH1A1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL29273437 | 0.74 | TSHR (0.58) | — | |
| Bromide SCHEMBL4960063 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL11828318 | 0.74 | TSHR (0.58) | — | |
| Hydrogen Sulfide SCHEMBL22129212 | 0.74 | — | — | |
| SCHEMBL30321461 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL2163448 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140915-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-05-02 | — | — | US | claimed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | claimed |
| US-20240058284-A1 | STAT3 INHIBITORS | TVARDI OPERATING COMPANY, INC. | 2024-02-22 | — | — | US | claimed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | claimed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| CN-110305072-B | Compounds with phosphodiesterase 4D and acid sphingomyelinase inhibitory activity and uses thereof | 中国药科大学 | 2023-09-19 | — | — | CN | claimed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | claimed |
| CN-116348450-A | Compounds, compositions and methods for histone lysine demethylase inhibition | 菲布罗根有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-114409611-A | Oxadiazole hydrazide compound and preparation method and application thereof | 贵州大学 | 2022-04-29 | — | — | CN | claimed |
| CN-113372334-A | 2- (4-methionyl) anilino-4-amino-5-trifluoromethylpyrimidine derivatives and application thereof | 贵州医科大学 | 2021-09-10 | — | — | CN | claimed |
| EP-0054217-A1 | Anthraquinone dyes, process for their preparation, their use, as well as liquid-crystal material containing anthraquinone dyes | BAYER AG (DE) | 1982-06-23 | — | — | EP | claimed |
| EP-0011928-B1 | 3,5-DIHYDROXYPENTANOIC ESTER DERIVATIVES HAVING ANTIHYPERLIPAEMIC ACTIVITY, THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1982-04-28 | — | — | EP | claimed |
| US-4310700-A | 1-Hydroxylmethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| US-4255444-A | ANTICHOLESTEROL AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-03-10 | — | — | US | claimed |
| US-4248889-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY LIMITED (JP) | 1981-02-03 | — | — | US | claimed |
| US-4241221-A | HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1980-12-23 | — | — | US | claimed |
| EP-0011928-A1 | 3,5-Dihydroxypentanoic ester derivatives having antihyperlipaemic activity, their manufacture and pharmaceutical compositions containing them | SANKYO COMPANY LIMITED (JP) | 1980-06-11 | — | — | EP | claimed |
| EP-0010951-A1 | 4-Hydroxy-2-pyrone derivatives, process for their preparation and their pharmaceutical preparations | SANKYO COMPANY LIMITED (JP) | 1980-05-14 | — | — | EP | claimed |
| EP-0010360-A1 | Prostane derivatives, processes for their preparation and their pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | claimed |
| US-4145540-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-20 | — | — | US | claimed |