Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | GBA1 | P04062 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3406093 | 0.98 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL451810 | 0.83 | CYP3A4 (0.69) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL8349568 | 0.81 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| Hydrochloric Acid SCHEMBL5015149 | 0.81 | CYP3A4 (0.67) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL6437093 | 0.79 | ALDH1A1 (0.75) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL5450999 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL11874029 | 0.78 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2GBA1CA1 | |
| SCHEMBL5323067 | 0.78 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL6671584 | 0.78 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2KDM4EPKM | |
| SCHEMBL3651548 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089763-A2 | AGENTS FOR SPECIFICALLY INHIBITING OSTEOCLASTIC BONE RESORPTION | Dietsch, Peter (DE) | 2001-04-11 | — | — | EP | claimed |
| WO-1999066910-A2 | AGENTS FOR SPECIFICALLY INHIBITING OSTEOCLASTIC BONE RESORPTION | DIETSCH PETER (DE) | 1999-12-29 | — | — | WO | claimed |
| US-20230146675-A1 | PYRIMIDO[5,4-d]PYRIMIDINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS | iTeos Belgium SA (BE) | 2023-05-11 | — | — | US | disclosed |
| CN-108047437-A | A kind of polyester fabric for being used to interweave with acetate fiber and preparation method thereof | 泉州禾伦织造有限公司 | 2018-05-18 | — | — | CN | disclosed |
| EP-3078640-A1 | BIO-CONVERSION OF REFINERY WASTE STREAMS | Indian Oil Corporation Limited (IN) | 2016-10-12 | — | — | EP | disclosed |
| US-9193990-B2 | Bioluminescent metal ion assay | Thompson, Richard B. (US) | 2015-11-24 | — | — | US | disclosed |
| CN-102300844-B | Sulfamoyl-phenyl-ureidobenzamidine derivatives as antimalarial agents | 4SC AG | 2015-03-11 | — | — | CN | disclosed |
| US-20140273038-A1 | BIOLUMINESCENT METAL ION ASSAY | Thompson, Richard B. (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2670764-A1 | C-28 AMINES OF C-3 MODIFIED BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-12-11 | — | — | EP | disclosed |
| WO-2012106188-A1 | C-28 AMINES OF C-3 MODIFIED BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-08-09 | — | — | WO | disclosed |
| WO-2010002998-A1 | 2,4,6-TRISUBSTITUTED PYRIDO (3,2-d) PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2002061066-A1 | METHOD FOR PRODUCING AN ENZYME FROM A NOVEL SOURCE | OULUN YLIOPISTO (FI) | 2002-08-08 | — | — | WO | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-0896541-A4 | — | — | 1999-03-24 | — | — | EP | disclosed |
| EP-0896541-A1 | SILVER-BASED PHARMACEUTICAL COMPOSITIONS | CAPELLI, Christopher C. (US) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997002038-A1 | SILVER-BASED PHARMACEUTICAL COMPOSITIONS | CAPELLI CHRISTOPHER C (US) | 1997-01-23 | — | — | WO | disclosed |
| EP-0673234-A4 | TISSUE PROTECTIVE AND REGENERATIVE COMPOSITIONS. | SKIN BIOLOGY INC (US) | 1996-12-27 | — | — | EP | disclosed |
| EP-0673234-A1 | TISSUE PROTECTIVE AND REGENERATIVE COMPOSITIONS | Skin Biology, Inc. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994007448-A1 | TISSUE PROTECTIVE AND REGENERATIVE COMPOSITIONS | SKIN SCIENCE INCORPORATED (US) | 1994-04-14 | — | — | WO | disclosed |
| WO-1992012635-A1 | METHODS OF TRANSCRIPTIONALLY MODULATING GENE EXPRESSION OF VIRAL GENES AND OTHER GENES | ONCOGENE SCIENCE, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146675-A1 | PYRIMIDO[5,4-d]PYRIMIDINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS | ENTPD5, ENTPD1, SLC29A1 | ALDH1A1 226/4885LMNA 4510/4885SMN1; SMN2 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.