Stearic Acid

Stearic Acid

SCHEMBL323989

CC(O)COC(C)CO.CCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.53

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Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.53
PPARG P37231 7/20 0.53
PPARD Q03181 7/20 0.53
PPARA Q07869 7/20 0.53
HDAC11 Q96DB2 5/20 0.53
TSHR P16473 4/20 0.53
PTPN1 P18031 3/20 0.53
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 2/20 0.53
TLR2 O60603 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
FABP4 P15090 2/20 0.53
FFAR1 O14842 2/20 0.53
FFAR4 Q5NUL3 2/20 0.53
MEN1 O00255 2/20 0.53
SLC22A6 Q4U2R8 1/20 0.53
SLC22A8 Q8TCC7 1/20 0.53
ESR1 P03372 1/20 0.53
ALOX15 P16050 1/20 0.53
PDE4A P27815 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptadecanoic Acid SCHEMBL28700376 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL8950265 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL15665487 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Azelaic Acid SCHEMBL7852023 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Pentadecanoic Acid SCHEMBL17668919 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL4895595 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL15665018 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL15665264 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Nonanoate SCHEMBL22721294 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Tridecanoate SCHEMBL29378854 1.00 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3795141-B1 SOLID SOLUTION COMPOSITIONS INFIRST HEALTHCARE LTD (GB) 2025-07-30 EP disclosed
US-20240277613-A1 Solid Solution Compositions and Use in Chronic Inflammation INFIRST HEALTHCARE LIMITED (GB) 2024-08-22 US disclosed
US-20240207408-A1 Solid Solution Compositions and Use in Severe Pain INFIRST HEALTHCARE LIMITED (GB) 2024-06-27 US disclosed
US-11992555-B2 Solid solution compositions and use in chronic inflammation INFIRST HEALTHCARE LIMITED (GB) 2024-05-28 US disclosed
US-11918654-B2 Solid solution compositions and use in severe pain INFIRST HEALTHCARE LIMITED (GB) 2024-03-05 US disclosed
US-11844773-B2 Solid solution compositions and use in chronic inflammation INFIRST HEALTHCARE LIMITED (GB) 2023-12-19 US disclosed
US-11826428-B2 Solid solution compositions comprising cannabidiols INFIRST HEALTHCARE LIMITED (GB) 2023-11-28 US disclosed
US-11730709-B2 Compositions and methods for treating severe pain INFIRST HEALTHCARE LIMITED (GB) 2023-08-22 US disclosed
US-20220118091-A1 Solid Solution Compositions and Use in Severe Pain INFIRST HEALTHCARE LIMITED (GB) 2022-04-21 US disclosed
US-20220096637-A1 Solid Solution Compositions and Use in Cardiovascular Disease INFIRST HEALTHCARE LIMITED (GB) 2022-03-31 US disclosed
CN-1957302-A Toner, method for producing toner, two-component developer, and image forming apparatus MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2007-05-02 CN disclosed
US-20050255397-A1 Resin particles and producing method thereof, toner for developing electrostatic latent image and producing method thereof, electrostatic latent image developer as well as image forming method FUJI XEROX CO., LTD. (JP) 2005-11-17 US disclosed
US-5508141-A AQUEOUS ACIDIC PHOTORESIST EMULSION CONTAINING RESIN, POSITIVE-ACTING PHOTOACTIVE FUNCTIONALITY, ACID, OXIDIZING AGENT, SURFACTANT W. R. GRACE & CO.-CONN. (US) 1996-04-16 US disclosed
CN-1030739-C Method for selectively coating metal surface, method for forming circuit pattern from metal surface and photosensitive emulsion used therefor GRACE W R & CO (US) 1996-01-17 CN disclosed
EP-0468002-A4 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES GRACE W R & CO (US) 1995-08-09 EP disclosed
US-5232815-A Corrosion resistance W. R. GRACE & CO.-CONN. (US) 1993-08-03 US disclosed
EP-0518453-A1 A method of making electrical circuit traces W.R. Grace & Co.-Conn. (US) 1992-12-16 EP disclosed
EP-0468002-A1 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES W.R. GRACE & CO.-CONN. (US) 1992-01-29 EP disclosed
CN-1054836-A Automatic deposition emulsion and the method for the metal surface being carried out selective protection with this emulsion GRACE W R & CO (US) 1991-09-25 CN disclosed
WO-1991008840-A1 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES W.R. GRACE & CO.-CONN. (US) 1991-06-27 WO disclosed