SCHEMBL3239972

SCHEMBL3239972

CCCCCCCCC=CCCCCCCCCOCC(COC(=O)NCCN(CC)CC)OCCCCCCCCC=CCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.47
TLR2 O60603 2/20 0.42
LPAR1 Q92633 2/20 0.42
LPAR3 Q9UBY5 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3239966 1.00 EPHX2 (0.47) EPHX2TLR2LPAR1LPAR3
SCHEMBL8004605 0.95 EPHX2 (0.49) EPHX2TLR2
SCHEMBL8004603 0.95 EPHX2 (0.49) EPHX2TLR2
SCHEMBL8013366 0.94 EPHX2 (0.44) EPHX2TLR2
SCHEMBL8013368 0.94 EPHX2 (0.44) EPHX2TLR2
SCHEMBL8015677 0.94 EPHX2 (0.47) EPHX2TLR2LPAR1LPAR3
SCHEMBL8015680 0.94 EPHX2 (0.47) EPHX2TLR2LPAR1LPAR3
SCHEMBL8014049 0.94 EPHX2 (0.47) EPHX2TLR2LPAR1LPAR3
SCHEMBL8014045 0.94 EPHX2 (0.47) EPHX2TLR2LPAR1LPAR3
SCHEMBL8020223 0.93 EPHX2 (0.43) EPHX2TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100152433-A1 ANTIVIRAL AGENT MICHINORI KOHARA (JP) 2010-06-17 US claimed
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP claimed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US claimed
EP-0685457-B1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU CO LTD (JP) 1999-12-15 EP claimed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP claimed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP claimed
WO-2023085440-A1 THERAPEUTIC AGENT FOR REFRACTORY VIRAL INFECTIONS 公益財団法人東京都医学総合研究所 2023-05-19 WO disclosed
US-20100152433-A1 ANTIVIRAL AGENT MICHINORI KOHARA (JP) 2010-06-17 US disclosed
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
EP-0685457-B1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU CO LTD (JP) 1999-12-15 EP disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152433-A1 ANTIVIRAL AGENT MAVS, SARS1, HAVCR2 EPHX2 2663/4885TLR2 815/4885LPAR1 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.