Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.68 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038931 | 1.00 | KIF11 (0.68) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL1042081 | 0.93 | KIF11 (0.72) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL1042594 | 0.93 | KIF11 (0.72) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL1041439 | 0.91 | KIF11 (0.81) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL3494904 | 0.91 | KIF11 (0.81) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL1040927 | 0.91 | KIF11 (0.62) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL1040835 | 0.90 | KIF11 (0.68) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL1042303 | 0.90 | KIF11 (0.68) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL3493835 | 0.90 | KIF11 (0.68) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL3496217 | 0.90 | KIF11 (0.72) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662581-B1 | Eg5 co-crystals | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2010-02-16 | — | — | US | disclosed |